Mechanochemical Multicomponent Synthesis

The growing demand for sustainable chemical processes has transformed modern organic synthesis, driving the adoption of green chemistry principles. This book presents a comprehensive overview of multicomponent mechanochemical synthesis as an environmentally benign approach for constructing organic and heterocyclic molecules. By integrating mechanochemistry with multicomponent reactions, solvent-free or solvent-minimized methodologies are highlighted that reduce waste, energy consumption, and environmental impact while maintaining high synthetic efficiency. The book covers mechanochemical strategies for carbon-carbon and carbon-heteroatom bond formation, as well as the synthesis of monocyclic and fused heterocycles. Emphasizing mechanistic insights, reaction scope, and practical applicability, this book serves as a valuable resource for sustainable organic synthesis.